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Sfrp4tm1.1Blan
Targeted Allele Detail
Nomenclature
Symbol: Sfrp4tm1.1Blan
Name: secreted frizzled-related protein 4; targeted mutation 1.1, Beate Lanske
MGI ID: MGI:5052054
Gene: Sfrp4  Location: Chr13:19623175-19632825 bp, + strand  Genetic Position: Chr13, 6.99 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:173962
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA loxP site was inserted 5' of the translation initiation site in exon 1 and a floxed neo cassette was inserted downstream of exon 1. Cre-mediated recombination removed exon 1. (J:173962)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sfrp4 Mutation:  11 strains or lines available
References
Original:  J:173962 Christov M, et al., Genetic ablation of sfrp4 in mice does not affect serum phosphate homeostasis. Endocrinology. 2011 May;152(5):2031-6
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory