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Targeted Allele Detail
Symbol: Birc3tm1Rbr
Name: baculoviral IAP repeat-containing 3; targeted mutation 1, Robert Brink
MGI ID: MGI:5013652
Synonyms: Birc3FRT, cIap2FRT
Gene: Birc3  Location: Chr9:7848699-7873186 bp, - strand  Genetic Position: Chr9, 2.46 cM, cytoband A2
Germline Transmission:  Earliest citation of germline transmission: J:172843
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsAn FRT site was inserted upstream of exon 2. An FRT-flanked neo cassette was inserted downstream of exon 3. (J:172843)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Birc3 Mutation:  7 strains or lines available
Original:  J:172843 Gardam S, et al., Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response. Blood. 2011 Apr 14;117(15):4041-51
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory