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Crispld2tm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Crispld2tm1Lex
Name: cysteine-rich secretory protein LCCL domain containing 2; targeted mutation 1, Lexicon Pharmaceuticals
MGI ID: MGI:5007091
Gene: Crispld2  Location: Chr8:119992438-120052793 bp, + strand  Genetic Position: Chr8, 68.76 cM, cytoband E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171883
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA portion of the coding region was targeted by homologous recombination. Exons 9,10, and 11 were targeted (NM_030209). Disruption of the target gene was confirmed by Southern hybridization analysis. (J:171883)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Crispld2 Mutation:  25 strains or lines available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory