All Phenotypes Crispld2<tm1Lex> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Crispld2^tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007091

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Crispld2^tm1Lex/Crispld2^tm1Lex	B6;129S5-Crispld2^tm1Lex/Mmucd	MGI:5828261

Allelic Composition	Crispld2^tm1Lex/Crispld2^tm1Lex
Genetic Background	B6;129S5-Crispld2^tm1Lex/Mmucd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crispld2^tm1Lex mutation (2 available); any Crispld2 mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

improved glucose tolerance ( J:171883 )

• male homozygous mutant mice show enhanced glucose tolerance at all 3 time intervals tested

immune system

abnormal immune system morphology ( J:171883 )

• homozygous mutant mice exhibit numerous immunological abnormalities when compared with controls

abnormal immune system physiology ( J:171883 )

• homozygous mutant mice exhibit numerous immunological abnormalities when compared with controls

skeleton

abnormal skeleton morphology ( J:171883 )

• male homozygous mutant mice show notably decreased bone-related measurements when compared with controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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