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Targeted Allele Detail
Symbol: Anp32btm1Mak
Name: acidic (leucine-rich) nuclear phosphoprotein 32 family, member B; targeted mutation 1, Tak Mak
MGI ID: MGI:5003050
Gene: Anp32b  Location: Chr4:46450902-46472657 bp, + strand  Genetic Position: Chr4, 24.79 cM, cytoband B2
Germline Transmission:  Earliest citation of germline transmission: J:172042
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 2, 3, and 4 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblast extracts. (J:172042)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Anp32b Mutation:  103 strains or lines available
Original:  J:172042 Reilly PT, et al., Acidic nuclear phosphoprotein 32kDa (ANP32)B-deficient mouse reveals a hierarchy of ANP32 importance in mammalian development. Proc Natl Acad Sci U S A. 2011 Jun 2;108(25):10243-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.10
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