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Pdcd10tm1Wami
Targeted Allele Detail
Nomenclature
Symbol: Pdcd10tm1Wami
Name: programmed cell death 10; targeted mutation 1, Wang Min
MGI ID: MGI:5002630
Synonyms: CCM3loxP, Pdcd10tm1Wmin
Gene: Pdcd10  Location: Chr3:75516490-75556852 bp, - strand  Genetic Position: Chr3, 33.76 cM, cytoband E3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171969
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129 and C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 4. A floxed neo cassette was inserted downstream of exon 5. (J:171969)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 17 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdcd10 Mutation:  7 strains or lines available
References
Original:  J:171969 He Y, et al., Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development. Sci Signal. 2010;3(116):ra26
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory