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Gmnntm1Tjm
Targeted Allele Detail
Nomenclature
Symbol: Gmnntm1Tjm
Name: geminin; targeted mutation 1, Thomas J MacGarry
MGI ID: MGI:4999617
Synonyms: Gmnnfl
Gene: Gmnn  Location: Chr13:24751845-24761923 bp, - strand  Genetic Position: Chr13, 10.64 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171741
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 5. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 7. (J:171741)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gmnn Mutation:  8 strains or lines available
References
Original:  J:171741 Shinnick KM, et al., Geminin deletion from hematopoietic cells causes anemia and thrombocytosis in mice. J Clin Invest. 2010 Dec 1;120(12):4303-15
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory