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Kcne3tm1Gwab
Targeted Allele Detail
Nomenclature
Symbol: Kcne3tm1Gwab
Name: potassium voltage-gated channel, Isk-related subfamily, gene 3; targeted mutation 1, Geoffrey W Abbott
MGI ID: MGI:4947550
Gene: Kcne3  Location: Chr7:100176502-100184869 bp, + strand  Genetic Position: Chr7, 54.33 cM, cytoband F1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:170745
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  B6(Cg)-Tyrc-2J
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA floxed neo cassette replaced exon 4. The absence of protein expression was confirmed by western blot analysis on colon extracts. (J:170745)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcne3 Mutation:  5 strains or lines available
Notes
ES cell line = C2J (Albino C57BL/6)
References
Original:  J:170745 Roepke TK, et al., Genetic dissection reveals unexpected influence of beta subunits on KCNQ1 K+ channel polarized trafficking in vivo. FASEB J. 2011 Feb;25(2):727-36
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory