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Csgalnact1tm1.1Nari
Targeted Allele Detail
Nomenclature
Symbol: Csgalnact1tm1.1Nari
Name: chondroitin sulfate N-acetylgalactosaminyltransferase 1; targeted mutation 1.1, Hisashi Narimatsu
MGI ID: MGI:4947395
Gene: Csgalnact1  Location: Chr8:68356781-68735146 bp, - strand  Genetic Position: Chr8, 33.88 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:170410
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 1. An FRT- and loxP-flanked neo cassette was inserted downstream of exon 1. Cre-mediated recombination removed exon 1 and the neo cassette. The absence of transcript expression was confirmed by real time PCR on brain extracts. (J:170410)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Csgalnact1 Mutation:  21 strains or lines available
References
Original:  J:170410 Sato T, et al., Chondroitin sulfate N-acetylgalactosaminyltransferase 1 is necessary for normal endochondral ossification and aggrecan metabolism. J Biol Chem. 2011 Feb 18;286(7):5803-12
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory