Wdr11^{Gt(Ayu21-KBW205)Imeg}
Gene trapped Allele Detail

Summary

• Symbol: Wdr11^{Gt(Ayu21-KBW205)Imeg}
• Name: WD repeat domain 11; gene trap Ayu21-KBW205, Institute of Molecular Embryology and Genetics
• MGI ID: MGI:4946808
• Synonyms: Wdr11^-
• Gene: Wdr11 Location: Chr7:129193587-129237462 bp, + strand Genetic Position: Chr7, 72.37 cM
• Alliance: Wdr11^{Gt(Ayu21-KBW205)Imeg} page

Mutation origin

• Mutant Cell Line: Ayu21-KBW205
• Germline Transmission: Earliest citation of germline transmission: J:257035
• Parent Cell Line: KAB6 (ES Cell)
• Strain of Origin: B6(Cg)-Tyr^c-2J/JCard

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: pU-21W
• Mutation details: Trapped gene association determined by genome coordinate overlap and strand. The pU-21W genetrap vector which contains a beta-galactosidase/neomycin phosphotransferase fusion gene with reduced CpG motifs, inserted in exon 3. Western blot analysis of total protein lysates from the brain and testis confirmed absence of protein in homozygotes. (J:257035)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  Ayu21-KBW205	AB624508 ; (MGI Seq Detail)	5' RACE	Chr7:129193655-129193786 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  2 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Structures Affected by this Mutation:

39 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wdr11 Mutation: 60 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 6 reference(s)