About   Help   FAQ
Maoatm1Shih
Targeted Allele Detail
Nomenclature
Symbol: Maoatm1Shih
Name: monoamine oxidase A; targeted mutation 1, Jean C Shih
MGI ID: MGI:4946240
Synonyms: MAO-Aneo
Gene: Maoa  Location: ChrX:16619698-16687818 bp, + strand  Genetic Position: ChrX, 11.78 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:170067
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 12. A floxed neo cassette was inserted downstream of exon 12. No enzymatic activity was detected. Removal of the neo cassette is required to restore enzymatic activity. (J:170067, J:193013)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Maoa Mutation:  7 strains or lines available
References
Original:  J:170067 Kaludercic N, et al., Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload. Circ Res. 2010 Jan 8;106(1):193-202
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/11/2017
MGI 6.10
The Jackson Laboratory