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Tg(CD2-Lck)1Rza
Transgene Detail
Summary
Symbol: Tg(CD2-Lck)1Rza
Name: transgene insertion 1, Rose Zamoyska
MGI ID: MGI:4946120
Synonyms: Lcktg
Transgene: Tg(CD2-Lck)1Rza  Location: unknown  
Alliance: Tg(CD2-Lck)1Rza page
Transgene
origin
Strain of Origin:  (CBA x C57BL/10)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CD2-Lck)1Rza expresses 1 gene
 
Mutation detailsThe transgene expresses a cDNA encoding the Lck gene, under the control of the human CD2 promoter. A C-terminal V5 epitope tag was added to the construct. (J:168430)
Tumor Data
List all tumor models in MMHCdb carrying Tg(CD2-Lck)1Rza
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:168430 Salmond RJ, et al., Mislocalization of Lck impairs thymocyte differentiation and can promote development of thymomas. Blood. 2011 Jan 6;117(1):108-17
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory