Gt(ROSA)26Sor^{tm1.1(FLII)Hdc}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1.1(FLII)Hdc}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Hugh D Campbell
• MGI ID: MGI:4939371
• Synonyms: R26R(FLII)U, RRFU
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1.1(FLII)Hdc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:168970
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: BALB/c

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1.1(FLII)Hdc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  FLII (2314)

  Flii	(MGI:1342286)

• Mutation details: Cre-mediated recombination removed the floxed stop cassette to allow for expression of the human cDNA. (J:168970)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:168970 Thomsen N, et al., Mouse strains for the ubiquitous or conditional overexpression of the Flii gene. Genesis. 2011 Aug;49(8):681-8
• All: 1 reference(s)