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Tg(CAG-Otx2,-GFP)21Asim
Transgene Detail
Nomenclature
Symbol: Tg(CAG-Otx2,-GFP)21Asim
Name: transgene insertion 21, Antonio Simeone
MGI ID: MGI:4887448
Synonyms: Tg(CAG-stop-Otx2,-GFP)21Asim, tOtx2bov
Transgene: Tg(CAG-Otx2,-GFP)21Asim  Location: unknown  Genetic Position: Chr7, Syntenic
Transgene
origin
Germline Transmission:  Earliest citation of germline transmission: J:143341
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-Otx2,-GFP)21Asim expresses 1 gene
 
Mutation detailsThe transgene, which contained a CAG promoter, floxed neo/STOP cassette, the Otx2 cDNA, and an IRES-GFP, was inserted using the Vectorette System (Sigma) 51 kb downstream of Isg20 and 111 kb upstream of Acan on chromosome 7 D2. No line number was given. (J:143341)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:143341 Omodei D, et al., Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon. Development. 2008 Oct;135(20):3459-70
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/17/2022
MGI 6.19
The Jackson Laboratory