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Ucp2tm2.1Lowl
Targeted Allele Detail
Nomenclature
Symbol: Ucp2tm2.1Lowl
Name: uncoupling protein 2 (mitochondrial, proton carrier); targeted mutation 2.1, Bradford B Lowell
MGI ID: MGI:4887236
Synonyms: Ucp2lox
Gene: Ucp2  Location: Chr7:100493337-100502020 bp, + strand  Genetic Position: Chr7, 54.36 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:167906
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ucp2 Mutation:  26 strains or lines available
References
Original:  J:167906 Kong D, et al., Glucose stimulation of hypothalamic MCH neurons involves K(ATP) channels, is modulated by UCP2, and regulates peripheral glucose homeostasis. Cell Metab. 2010 Nov 3;12(5):545-52
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory