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Ccr2tm2.1Ifc
Targeted Allele Detail
Nomenclature
Symbol: Ccr2tm2.1Ifc
Name: chemokine (C-C motif) receptor 2; targeted mutation 2.1, Israel F Charo
MGI ID: MGI:4868431
Synonyms: Ccr2R, Ccr2RFP
Gene: Ccr2  Location: Chr9:124101918-124109140 bp, + strand  Genetic Position: Chr9, 75.05 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166664
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding region was replaced with an RFP and floxed neo cassette. Cre-mediated recombination removed the neo cassette. The absence of transcript expression was confirmed by RT-PCR. (J:166664)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ccr2 Mutation:  27 strains or lines available
References
Original:  J:166664 Saederup N, et al., Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice. PLoS One. 2010;5(10):e13693
All:  118 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory