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Tfpitm1.1Rdsi
Targeted Allele Detail
Nomenclature
Symbol: Tfpitm1.1Rdsi
Name: tissue factor pathway inhibitor; targeted mutation 1.1, Robert D Simari
MGI ID: MGI:4836740
Gene: Tfpi  Location: Chr2:84432855-84476775 bp, - strand  Genetic Position: Chr2, 49.41 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:164530
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA FRT flanked Neomycin cassette was inserted within intron 3 and exon 4 was floxed by homologous recombination. The selection cassette was removed by flp mediated recombination. (J:164530)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tfpi Mutation:  23 strains or lines available
References
Original:  J:164530 White TA, et al., Endothelial-derived tissue factor pathway inhibitor regulates arterial thrombosis but is not required for development or hemostasis. Blood. 2010 Sep 9;116(10):1787-94
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory