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Cd44tm2.1Ugu
Targeted Allele Detail
Nomenclature
Symbol: Cd44tm2.1Ugu
Name: CD44 antigen; targeted mutation 2.1, Ursula Gunthert
MGI ID: MGI:4835490
Synonyms: CD44v10-/-, CD44v10-/-
Gene: Cd44  Location: Chr2:102811141-102901665 bp, - strand  Genetic Position: Chr2, 54.13 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82809
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele was generated from Cd44tm2Ugu by Cre recombinase excision of the neomycin resistance cassette and exon 10. (J:199279)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 6 strains available      Cell Lines: 0 lines available
Carrying any Cd44 Mutation:  32 strains or lines available
References
Original:  J:199279 Ghazi-Visser L, et al., CD44 variant isoforms control experimental autoimmune encephalomyelitis by affecting the lifespan of the pathogenic T cells. FASEB J. 2013 Sep;27(9):3683-701
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory