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Tg(PER2*S662D)405Ljp
Transgene Detail
Nomenclature
Symbol: Tg(PER2*S662D)405Ljp
Name: transgene insertion 405, Louis J Ptacek
MGI ID: MGI:4833973
Synonyms: hPer2 S662D
Transgene: Tg(PER2*S662D)405Ljp  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(PER2*S662D)405Ljp expresses 1 gene
 
Mutation detailsThe full-length sequence of the human PER2 gene carried in BAC RP11-139K17 was modified to change serine residue 662 to aspartic acid (S662D, AGT->GAT). Several lines were generated. (J:126404)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:126404 Xu Y, et al., Modeling of a human circadian mutation yields insights into clock regulation by PER2. Cell. 2007 Jan 12;128(1):59-70
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory