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Gys2tm1.1Pro
Targeted Allele Detail
Nomenclature
Symbol: Gys2tm1.1Pro
Name: glycogen synthase 2; targeted mutation 1.1, Peter J Roach
MGI ID: MGI:4462836
Synonyms: Gys2(Lox)
Gene: Gys2  Location: Chr6:142422613-142473109 bp, - strand  Genetic Position: Chr6, 74.04 cM
Decreased glycogen liver content in Gys2tm1.1Pro/Gys2tm1.1Pro Tg(Alb-cre)21Mgn/0 mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:162043
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Generation of the floxed Gys2tm1.1Pro allele
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gys2 Mutation:  1 strain or line available
References
Original:  J:162043 Irimia JM, et al., Impaired glucose tolerance and predisposition to the fasted state in liver glycogen synthase knock-out mice. J Biol Chem. 2010 Apr 23;285(17):12851-61
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory