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Srpk2tm1Nik
Targeted Allele Detail
Nomenclature
Symbol: Srpk2tm1Nik
Name: serine/arginine-rich protein specific kinase 2; targeted mutation 1, Nigel Killeen
MGI ID: MGI:4460670
Gene: Srpk2  Location: Chr5:23503356-23616571 bp, - strand  Genetic Position: Chr5, 10.36 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:161558
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsA puro cassette, loxP site, and 3'Hprt minigene with IRES GFP were inserted into intron 14-15 duplicating part of the gene. (J:161558)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Srpk2 Mutation:  10 strains or lines available
References
Original:  J:161558 Wong JC, et al., Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies. Blood. 2010 Jun 3;115(22):4524-32
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory