Il17rb^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Il17rb^tm1Lex
• Name: interleukin 17 receptor B; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:4459522
• Gene: Il17rb Location: Chr14:29718125-29730853 bp, - strand Genetic Position: Chr14, 18.39 cM
• Alliance: Il17rb^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159874
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1-4 encompassing the Il-17rb coding sequence were replaced with a LacZ reporter and neomycin resistance cassette. (J:159874)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Il17rb Mutation: 41 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:159874 Hu Y, et al., IL-17RC is required for IL-17A- and IL-17F-dependent signaling and the pathogenesis of experimental autoimmune encephalomyelitis. J Immunol. 2010 Apr 15;184(8):4307-16
• All: 2 reference(s)