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Nr3c1tm2.1Ljm
Targeted Allele Detail
Nomenclature
Symbol: Nr3c1tm2.1Ljm
Name: nuclear receptor subfamily 3, group C, member 1; targeted mutation 2.1, Louis J Muglia
MGI ID: MGI:4456461
Synonyms: GrloxP, Nr3c1flox, Nr3c1flox
Gene: Nr3c1  Location: Chr18:39410545-39519421 bp, - strand  Genetic Position: Chr18, 21.09 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97484
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Cre mediated recombination removed the neo cassette leaving exons 1c through exon 2 floxed. (J:97484)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nr3c1 Mutation:  21 strains or lines available
References
Original:  J:97484 Brewer JA, et al., T-cell glucocorticoid receptor is required to suppress COX-2-mediated lethal immune activation. Nat Med. 2003 Oct;9(10):1318-22
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/03/2020
MGI 6.15
The Jackson Laboratory