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Ltbrtm1Avt
Targeted Allele Detail
Nomenclature
Symbol: Ltbrtm1Avt
Name: lymphotoxin B receptor; targeted mutation 1, Alexei V Tumanov
MGI ID: MGI:4453317
Gene: Ltbr  Location: Chr6:125306571-125313885 bp, - strand  Genetic Position: Chr6, 59.32 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158663
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted 5' of exon 1 and a third loxP site was inserted within intron 2 via homologous recombination. (J:158663)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ltbr Mutation:  4 strains or lines available
References
Original:  J:158663 Wang Y, et al., Lymphotoxin beta receptor signaling in intestinal epithelial cells orchestrates innate immune responses against mucosal bacterial infection. Immunity. 2010 Mar 26;32(3):403-13
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory