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Mapk8tm1Jcbr
Targeted Allele Detail
Nomenclature
Symbol: Mapk8tm1Jcbr
Name: mitogen-activated protein kinase 8; targeted mutation 1, Jens Bruning
MGI ID: MGI:4441327
Synonyms: JNK1fl
Gene: Mapk8  Location: Chr14:33377898-33447158 bp, - strand  Genetic Position: Chr14, 20.22 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158650
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn frt flanked neo cassette with a 5' loxP site was inserted upstream of exon 2 and a loxP site was inserted downstream of exon 2. (J:158650)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapk8 Mutation:  39 strains or lines available
References
Original:  J:158650 Belgardt BF, et al., Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6028-33
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory