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Ahi1tm2.1Jgg
Targeted Allele Detail
Nomenclature
Symbol: Ahi1tm2.1Jgg
Name: Abelson helper integration site 1; targeted mutation 2.1, Joseph G Gleeson
MGI ID: MGI:4437788
Gene: Ahi1  Location: Chr10:20952547-21080429 bp, + strand  Genetic Position: Chr10, 9.75 cM, cytoband A3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158019
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 6 and a floxed neo cassette was inserted downstream of exon 7. Cre-mediated recombination removed the neo cassette leaving exon 6 through 7 floxed. (J:158019)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ahi1 Mutation:  13 strains or lines available
References
Original:  J:158019 Louie CM, et al., AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis. Nat Genet. 2010 Feb;42(2):175-80
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory