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Cidectm1a(EUCOMM)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Cidectm1a(EUCOMM)Wtsi
Name: cell death-inducing DFFA-like effector c; targeted mutation 1a, Wellcome Trust Sanger Institute
MGI ID: MGI:4433521
Gene: Cidec  Location: Chr6:113424634-113435760 bp, - strand  Genetic Position: Chr6, 52.76 cM, cytoband E3
Mutation
origin
Mutant Cell Lines:  EPD0116_3_A05, EPD0116_3_B05, EPD0116_3_B06, EPD0116_3_B07, EPD0116_3_C07, EPD0116_3_D05, EPD0116_3_D06, EPD0116_3_E05, EPD0116_3_E06, EPD0116_3_E07, EPD0116_3_F05, EPD0116_3_F06, EPD0116_3_G06, EPD0116_3_H05 (Wellcome Trust Sanger Institute)
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_Bact_P
 
Mutation detailsThe L1L2_Bact_P cassette was inserted at position 113433637 of Chromosome 6 upstream of the critical exon(s) (Build GRCm38). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 113432780. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other KOMP alleles can be found at http://www.knockoutmouse.org/aboutkompstrategies. (J:155845, J:173534)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cidec Mutation:  6 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory