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Wwoxtm1Mald
Targeted Allele Detail
Nomenclature
Symbol: Wwoxtm1Mald
Name: WW domain-containing oxidoreductase; targeted mutation 1, Marcelo Aldaz
MGI ID: MGI:4415791
Synonyms: Wwoxflox
Gene: Wwox  Location: Chr8:115166395-116079447 bp, + strand  Genetic Position: Chr8, 60.99 cM, cytoband E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155406
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn frt flanked neo cassette with a 5' loxP site was inserted upstream of exon 1 and an additional loxP site was inserted downstream of the exon. (J:155406)
Generation of the Wwoxtm1Mald allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wwox Mutation:  46 strains or lines available
References
Original:  J:155406 Ludes-Meyers JH, et al., Generation and characterization of mice carrying a conditional allele of the Wwox tumor suppressor gene. PLoS One. 2009;4(11):e7775
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory