About   Help   FAQ
Targeted Allele Detail
Symbol: Wwoxtm1Mald
Name: WW domain-containing oxidoreductase; targeted mutation 1, Marcelo Aldaz
MGI ID: MGI:4415791
Synonyms: Wwoxflox
Gene: Wwox  Location: Chr8:115166395-116079447 bp, + strand  Genetic Position: Chr8, 60.99 cM, cytoband E1
Germline Transmission:  Earliest citation of germline transmission: J:155406
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsAn frt flanked neo cassette with a 5' loxP site was inserted upstream of exon 1 and an additional loxP site was inserted downstream of the exon. (J:155406)
Generation of the Wwoxtm1Mald allele
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wwox Mutation:  46 strains or lines available
Original:  J:155406 Ludes-Meyers JH, et al., Generation and characterization of mice carrying a conditional allele of the Wwox tumor suppressor gene. PLoS One. 2009;4(11):e7775
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.17
The Jackson Laboratory