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Elavl1tm1.1Thla
Targeted Allele Detail
Nomenclature
Symbol: Elavl1tm1.1Thla
Name: ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R); targeted mutation 1.1, Timothy Hla
MGI ID: MGI:4414854
Gene: Elavl1  Location: Chr8:4285382-4325413 bp, - strand  Genetic Position: Chr8, 2.0 cM
Elavl1tm1.1Thla/Elavl1+ mice have increased sensitivity to whole-body irradiation

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155109
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 2 through 5 were removed by cre mediated recombination. (J:155109)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Elavl1 Mutation:  26 strains or lines available
References
Original:  J:155109 Ghosh M, et al., Essential role of the RNA-binding protein HuR in progenitor cell survival in mice. J Clin Invest. 2009 Dec;119(12):3530-43
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/15/2017
MGI 6.10
The Jackson Laboratory