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| Caption | Elavl1tm1.1Thla/Elavl1+ (Elavl1+/-) mice have increased sensitivity to whole-body irradiation. (A) A schematic of wild-type (Elavl1+/+; WT) and heterozygous mutant mice exposed to radiation. (B) Total cell number in bone marrow (BM), spleen, and thymus in nonirradiated WT and mutant mice (n = 3). (C) H&E stain of bone and spleen tissue sections from WT and mutant mice before and after irradiation. Original magnification, 10 (spleen); 40 (BM). Scale bar: 20 um (BM); 100 um (spleen). (D) Total number of cells isolated from BM, spleen, and thymus of irradiated WT and mutant mice (n >/= 5). Horizontal bars indicate mean of data points, and each dot represents an analyzed mouse (B and D). | ||||
| Copyright | This image is from Ghosh M, J Clin Invest 2009 Dec;119(12):3530-43 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:155109 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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