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Nkx6-2tm1(cre/ERT2)Fsh
Targeted Allele Detail
Nomenclature
Symbol: Nkx6-2tm1(cre/ERT2)Fsh
Name: NK6 homeobox 2; targeted mutation 1, Gordon Fishell
MGI ID: MGI:4412372
Synonyms: Nkx6-2CreER, Nkx6-2tm1.1(cre/ERT2)Fsh
Gene: Nkx6-2  Location: Chr7:139159292-139162713 bp, - strand  Genetic Position: Chr7, 84.57 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155164
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
    Exons 1 and 2 were replaced with a cre/ERT2 fusion and floxed self-excising neo cassette. (J:155164)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nkx6-2     Summary of all recombinase alleles driven by Nkx6-2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nkx6-2 Mutation:  11 strains or lines available
References
Original:  J:155164 Sousa VH, et al., Characterization of Nkx6-2-derived neocortical interneuron lineages. Cereb Cortex. 2009 Jul;19 Suppl 1:i1-10
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory