Sdcbptm1a(KOMP)Wtsi
Targeted Allele Detail
|
Symbol: |
Sdcbptm1a(KOMP)Wtsi |
Name: |
syndecan binding protein; targeted mutation 1a, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:4363272 |
Gene: |
Sdcbp Location: Chr4:6365654-6396122 bp, + strand Genetic Position: Chr4, 2.91 cM, cytoband A1
|
Alliance: |
Sdcbptm1a(KOMP)Wtsi page
|
IMPC: |
Sdcbp gene page |
|
Mutant Cell Lines: |
EPD0019_2_A01, EPD0019_2_A02, EPD0019_2_B02, EPD0019_2_B03, EPD0019_2_C02, EPD0019_2_D02, EPD0019_2_E01, EPD0019_2_E02, EPD0019_2_F03, EPD0019_2_G02, EPD0019_2_H01, EPD0019_2_H02, EPD0019_2_H03 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204812
|
Parent Cell Line: |
JM8 (ES Cell)
|
Strain of Origin: |
C57BL/6N
|
Project Collection: |
KOMP-CSD
|
|
Allele Type: |
|
Targeted (Conditional ready, Null/knockout, Reporter) |
Mutation: |
|
Insertion
Vector: L1L2_st0
|
|
|
Mutation details: The L1L2_st0 cassette was inserted at position 6378514 of Chromosome 4 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 6379337. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:148605, J:173534)
|
|
|
|
Original: |
J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009; |
All: |
5 reference(s) |
|