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Camk2btm1Yelg
Targeted Allele Detail
Nomenclature
Symbol: Camk2btm1Yelg
Name: calcium/calmodulin-dependent protein kinase II, beta; targeted mutation 1, Ype Elgersma
MGI ID: MGI:4359775
Synonyms: Camk2b-
Gene: Camk2b  Location: Chr11:5969644-6066362 bp, - strand  Genetic Position: Chr11, 3.89 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152575
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsMost of exon 11 and part of intron 11 were replaced with a floxed neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:152575)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Camk2b Mutation:  73 strains or lines available
References
Original:  J:152575 van Woerden GM, et al., betaCaMKII controls the direction of plasticity at parallel fiber-Purkinje cell synapses. Nat Neurosci. 2009 Jul;12(7):823-5
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory