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Grk4tm1Rjl
Targeted Allele Detail
Nomenclature
Symbol: Grk4tm1Rjl
Name: G protein-coupled receptor kinase 4; targeted mutation 1, Robert J Lefkowitz
MGI ID: MGI:4359726
Synonyms: GRK4 KO
Gene: Grk4  Location: Chr5:34817723-34912649 bp, + strand  Genetic Position: Chr5, 17.91 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152745
Parent Cell Line:  AK7 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A NsiI fragment containing exon 7 was replaced with a neomycin resistance cassette. (J:152745)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Grk4 Mutation:  16 strains or lines available
References
Original:  J:152745 Lefkowitz RJ, Generation of a Grk4 knockout allele. MGI Direct Data Submission. 2009;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory