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Klf2tm2Ling
Targeted Allele Detail
Nomenclature
Symbol: Klf2tm2Ling
Name: Kruppel-like factor 2 (lung); targeted mutation 2, Jerry B Lingrel
MGI ID: MGI:4355063
Synonyms: Klf2fl
Gene: Klf2  Location: Chr8:72319062-72321654 bp, + strand  Genetic Position: Chr8, 34.99 cM, cytoband C1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:151604
Parent Cell Line:  Duffy (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    LoxP sites were inserted into introns 1 and 2 of the gene locus (J:151604, J:212516)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Klf2 Mutation:  7 strains or lines available
References
Original:  J:151604 Weinreich MA, et al., KLF2 transcription-factor deficiency in T cells results in unrestrained cytokine production and upregulation of bystander chemokine receptors. Immunity. 2009 Jul 17;31(1):122-30
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory