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Cacna1gtm1.3Ksak
Targeted Allele Detail
Nomenclature
Symbol: Cacna1gtm1.3Ksak
Name: calcium channel, voltage-dependent, T type, alpha 1G subunit; targeted mutation 1.3, Kenji Sakimura
MGI ID: MGI:4354305
Synonyms: alpha1G-, Cacna1gtm1.1Abp
Gene: Cacna1g  Location: Chr11:94408391-94474198 bp, - strand  Genetic Position: Chr11, 58.9 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:151612
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Germline, cre mediated recombination removed the neo cassette and exon 5. (J:151612)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cacna1g Mutation:  60 strains or lines available
References
Original:  J:151612 Petrenko AB, et al., Mutation of alpha1G T-type calcium channels in mice does not change anesthetic requirements for loss of the righting reflex and minimum alveolar concentration but delays the onset of anesthetic induction. Anesthesiology. 2007 Jun;106(6):1177-85
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory