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Asic3tm1Pho
Targeted Allele Detail
Nomenclature
Symbol: Asic3tm1Pho
Name: acid-sensing (proton-gated) ion channel 3; targeted mutation 1, Peter Holzer
MGI ID: MGI:4353615
Synonyms: ASIC#-
Gene: Asic3  Location: Chr5:24413392-24417835 bp, + strand  Genetic Position: Chr5, 11.72 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:151304
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA floxed neomycin cassette replaced part of exon 1, and all of exons 2-7. Southern blotting confirmed correct targeting took place. (J:151304)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Asic3 Mutation:  16 strains or lines available
References
Original:  J:151304 Wultsch T, et al., Deletion of the acid-sensing ion channel ASIC3 prevents gastritis-induced acid hyperresponsiveness of the stomach-brainstem axis. Pain. 2008 Feb;134(3):245-53
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory