About   Help   FAQ
Gene trapped Allele Detail
Symbol: SucoGt(KST050)Byg
Name: SUN domain containing ossification factor; gene trap KST050, BayGenomics
MGI ID: MGI:4123936
Gene: Suco  Location: Chr1:161816114-161876682 bp, - strand  Genetic Position: Chr1, 69.95 cM
SucoGt(KST050)Byg/SucoGt(KST050)Byg mice exhibit growth retardation and low bone mass with multiple fractures

Show the 3 phenotype image(s) involving this allele.

Mutant Cell Line:  KST050 (BayGenomics)
Germline Transmission:  Earliest citation of germline transmission: J:159823
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT0TMpf     Vector Type: secretory trap
Mutation detailsThe gene trap vector inserted at bp 1624 in intron 11. RT-PCR and northern blot analysis confirmed the absence of full length transcript in homozygous embryos. Immunoblot analysis detected negligible amounts of protein in homozygous whole embryo lysates. Beta-galactosidase activity was detected in all skeletal elements of newborn heterozygotes. (J:159823)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Suco Mutation:  5 strains or lines available
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.01
The Jackson Laboratory