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Gene trapped Allele Detail
Symbol: SucoGt(KST050)Byg
Name: SUN domain containing ossification factor; gene trap KST050, BayGenomics
MGI ID: MGI:4123936
Gene: Suco  Location: Chr1:161816114-161876682 bp, - strand  Genetic Position: Chr1, 69.95 cM
SucoGt(KST050)Byg/SucoGt(KST050)Byg mice exhibit growth retardation and low bone mass with multiple fractures

Show the 3 phenotype image(s) involving this allele.

Mutant Cell Line:  KST050 (BayGenomics)
Germline Transmission:  Earliest citation of germline transmission: J:159823
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT0TMpf     Vector Type: secretory trap
Mutation detailsThe gene trap vector inserted at bp 1624 in intron 11. RT-PCR and northern blot analysis confirmed the absence of full length transcript in homozygous embryos. Immunoblot analysis detected negligible amounts of protein in homozygous whole embryo lysates. Beta-galactosidase activity was detected in all skeletal elements of newborn heterozygotes. (J:159823)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Suco Mutation:  21 strains or lines available
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  3 reference(s)

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last database update
MGI 6.03
The Jackson Laboratory