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Sun2tm1Mhan
Targeted Allele Detail
Nomenclature
Symbol: Sun2tm1Mhan
Name: Sad1 and UNC84 domain containing 2; targeted mutation 1, Min Han
MGI ID: MGI:3850087
Synonyms: Sun2-
Gene: Sun2  Location: Chr15:79724070-79742536 bp, - strand  Genetic Position: Chr15, 37.85 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:150047
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 11 through 16 were replaced with a neo cassette. The absence of protein expression was confirmed by immunohistochemistry on muscle fiber samples. (J:150047)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 22 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sun2 Mutation:  31 strains or lines available
References
Original:  J:150047 Lei K, et al., SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice. Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10207-12
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory