About   Help   FAQ
Tmem27tm1Thu
Targeted Allele Detail
Nomenclature
Symbol: Tmem27tm1Thu
Name: transmembrane protein 27; targeted mutation 1, Thu H Le
MGI ID: MGI:3846424
Synonyms: collectrin-, NX-17-
Gene: Tmem27  Location: ChrX:164088830-164118860 bp, + strand  Genetic Position: ChrX, 76.12 cM, cytoband F5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:148752
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsMost of exon 4 and all of exon 5 were replaced with a neomycin cassette. Gene inactivation was confirmed by a lack of immunohistochemical signal in hemizygous null kidney cortex. (J:148752)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmem27 Mutation:  8 strains or lines available
References
Original:  J:148752 Malakauskas SM, et al., Aminoaciduria and altered renal expression of luminal amino acid transporters in mice lacking novel gene collectrin. Am J Physiol Renal Physiol. 2007 Feb;292(2):F533-44
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/05/2017
MGI 6.11
The Jackson Laboratory