Bmpertm1Cpat
Targeted Allele Detail
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Symbol: |
Bmpertm1Cpat |
Name: |
BMP-binding endothelial regulator; targeted mutation 1, Cam Patterson |
MGI ID: |
MGI:3840517 |
Gene: |
Bmper Location: Chr9:23134372-23396496 bp, + strand Genetic Position: Chr9, 9.55 cM, cytoband A4
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Alliance: |
Bmpertm1Cpat page
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Delayed branching morphogenesis and inadequately expanded alveoli in Bmpertm1Cpat/Bmper+ lungs
Show the 3 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:146800
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exons 1 and 2 were replaced with an EGFP and MC1r/neo cassette. The absence of transcript expression was confirmed by western blot analysis on lungs and heart extracts.
(J:146800)
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Generation of the Bmpertm1Cpat allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Bmper Mutation: |
47 strains or lines available
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Original: |
J:146800 Kelley R, et al., A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling. J Cell Biol. 2009 Feb 23;184(4):597-609 |
All: |
6 reference(s) |
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