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Targeted Allele Detail
Symbol: Dektm1Siwe
Name: DEK proto-oncogene (DNA binding); targeted mutation 1, Susanne I Wells
MGI ID: MGI:3838711
Gene: Dek  Location: Chr13:47084775-47106201 bp, - strand  Genetic Position: Chr13, 24.5 cM, cytoband B1
Germline Transmission:  Earliest citation of germline transmission: J:146608
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsA cassette containing IRES-lacZ-neo was inserted into exon 6. The absence of protein expression was confirmed by western blot analysis on primary keratinocytes and bone marrow. (J:146608)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dek Mutation:  12 strains or lines available
Original:  J:146608 Wise-Draper TM, et al., Overexpression of the cellular DEK protein promotes epithelial transformation in vitro and in vivo. Cancer Res. 2009 Mar 1;69(5):1792-9
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory