Snai1^tm1.1Stjw
Targeted Allele Detail

Summary

• Symbol: Snai1^tm1.1Stjw
• Name: snail family zinc finger 1; targeted mutation 1.1, Stephen Weiss
• MGI ID: MGI:3838175
• Synonyms: Snai1^fl, Snai1^tm2Stjw
• Gene: Snai1 Location: Chr2:167380115-167384734 bp, + strand Genetic Position: Chr2, 87.33 cM
• Alliance: Snai1^tm1.1Stjw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:146645
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A loxP site was inserted upstream of exon 3, and an frt flanked neo cassette with a 5' loxP site was inserted downstream of exon 3. Germ line, flp mediated recombination was used to remove the neo cassette leaving exon 3 floxed. (J:146645)

Generation of the Snai1^tm1.1Stjw allele

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Snai1 Mutation: 9 strains or lines available

References

• Original: J:146645 Rowe RG, et al., Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs. J Cell Biol. 2009 Feb 9;184(3):399-408
• All: 17 reference(s)