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Pirttm1Xzd
Targeted Allele Detail
Nomenclature
Symbol: Pirttm1Xzd
Name: phosphoinositide-interacting regulator of transient receptor potential channels; targeted mutation 1, Xinzhong Dong
MGI ID: MGI:3834636
Synonyms: Pirt-
Gene: Pirt  Location: Chr11:66911981-66929876 bp, + strand  Genetic Position: Chr11, 40.59 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:145300
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe open reading frame was replaced with a farnesylated EGFP, an IRES-reverse tetracylcine transactivatior (IRES-rtTA), and a self-excising neo cassette. (J:145300)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pirt Mutation:  7 strains or lines available
References
Original:  J:145300 Kim AY, et al., Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1. Cell. 2008 May 2;133(3):475-85
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory