Eya3^{Gt(W096D02)Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Eya3^{Gt(W096D02)Wrst}
• Name: EYA transcriptional coactivator and phosphatase 3; gene trap W096D02, Wolfgang Wurst
• MGI ID: MGI:3834107
• Gene: Eya3 Location: Chr4:132366303-132452076 bp, + strand Genetic Position: Chr4, 65.68 cM
• Alliance: Eya3^{Gt(W096D02)Wrst} page

Mutation origin

• Mutant Cell Line: W096D02
• Germline Transmission: Earliest citation of germline transmission: J:145164
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pT1betageo
• Mutation details: The gene trap vector pT1betageo, which contains a promoterless lacZ gene, was inserted downstream of exon 7. The absence of exons 8 through 15 in the transcript was confirmed by RT-PCR on E11.5 whole embryo, E13.5 head and E15.5 head extracts. (J:145164)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  W096D02	CL211739 ; (MGI Seq Detail)	5' RACE	Chr4:132437287-132439255 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  394 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	67 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Eya3 Mutation: 400 strains or lines available

References

• Original: J:145164 Soker T, et al., Pleiotropic effects in Eya3 knockout mice. BMC Dev Biol. 2008 Dec 22;8(1):118
• All: 2 reference(s)