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Rad50tm3Jpt
Targeted Allele Detail
Nomenclature
Symbol: Rad50tm3Jpt
Name: RAD50 homolog (S. cerevisiae); targeted mutation 3, John H J Petrini
MGI ID: MGI:3832533
Synonyms: Rad50ind
Gene: Rad50  Location: Chr11:53649519-53707319 bp, - strand  Genetic Position: Chr11, 31.98 cM, cytoband A5-B1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:144766
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA puromycin resistance cassette with a 5' loxP site was inserted upstream of exon 1, and an additional loxP site was inserted downstream of exon 2. (J:144766)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rad50 Mutation:  5 strains or lines available
References
Original:  J:144766 Adelman CA, et al., Rad50 is dispensable for the maintenance and viability of postmitotic tissues. Mol Cell Biol. 2009 Jan;29(2):483-92
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory