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Tg(SFTPC-ITGB6)1Des
Transgene Detail
Nomenclature
Symbol: Tg(SFTPC-ITGB6)1Des
Name: transgene insertion 1, Dean Sheppard
MGI ID: MGI:3832271
Transgene: Tg(SFTPC-ITGB6)1Des  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(SFTPC-ITGB6)1Des expresses 1 gene
 
Mutation detailsExpression of a full length human ITGB6 cDNA was placed under the control of the human SFTPC promoter. The small t intron and polyadenylation sequence from SV40 were place 3' to the ITGB6 cDNA. (J:51592)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:51592 Huang X, et al., Expression of the human integrin beta6 subunit in alveolar type II cells and bronchiolar epithelial cells reverses lung inflammation in beta6 knockout mice. Am J Respir Cell Mol Biol. 1998 Oct;19(4):636-42
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory