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Tg(Pbsn-Ar*E231G)7353Ng
Transgene Detail
Summary
Symbol: Tg(Pbsn-Ar*E231G)7353Ng
Name: transgene insertion 7353, Norman M Greenberg
MGI ID: MGI:3831171
Synonyms: AR-E231G, PB-ARE231G, PB-AR(E231G)
Transgene: Tg(Pbsn-Ar*E231G)7353Ng  Location: unknown  
Alliance: Tg(Pbsn-Ar*E231G)7353Ng page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Pbsn-Ar*E231G)7353Ng expresses 1 gene
 
Mutation detailsA transgenic construct containing the mutant mouse androgen receptor (Ar), E231G, under the control of the minimal -426/+28 rat probasin promoter, a rabbit beta-globin sequence fragment, a bovine growth hormone polyadenylation site sequence and an N-terminal hemagglutinin (HA) epitope tag was injected into fertilized FVB/N mouse eggs. Seven lines were generated and founder line 7353 was established. (J:96117)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Tumor Data
List all tumor models in MMHCdb carrying Tg(Pbsn-Ar*E231G)7353Ng
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:96117 Han G, et al., Mutation of the androgen receptor causes oncogenic transformation of the prostate. Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1151-6
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory