Apod^tm1Dsan
Targeted Allele Detail

Summary

• Symbol: Apod^tm1Dsan
• Name: apolipoprotein D; targeted mutation 1, Diego Sanchez
• MGI ID: MGI:3829240
• Gene: Apod Location: Chr16:31115010-31133626 bp, - strand Genetic Position: Chr16, 21.41 cM
• Alliance: Apod^tm1Dsan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143809
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: An inverted neo cassette was inserted into exon 6 via homologous recombination. PCR, northern blot, and immunohistocheical analysis confirm the absence of RNA and protein expression in homozygotes. (J:143809)

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Apod Mutation: 19 strains or lines available

References

• Original: J:143809 Ganfornina MD, et al., Apolipoprotein D is involved in the mechanisms regulating protection from oxidative stress. Aging Cell. 2008 Aug;7(4):506-15
• All: 6 reference(s)