About   Help   FAQ
Pcdhgtm2Xzw
Targeted Allele Detail
Nomenclature
Symbol: Pcdhgtm2Xzw
Name: protocadherin gamma cluster; targeted mutation 2, Xiaozhong Wang
MGI ID: MGI:3821773
Synonyms: Pcdh-gammafcon3, Pcdhgfcon3, Pcdhgtm2Jrs
Gene: Pcdhg  Location: unknown  Genetic Position: Chr18, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:142186
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe Pcdh-gamma targeting vector was designed to insert a loxP site upstream of constant exon 3 of gamma-protocadherin (Pcdh-gamma) which was fused to EGFP, followed by a loxP-flanked PGK-neomycin resistance (neo) cassette. (J:142186)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pcdhg Mutation:  10 strains or lines available
References
Original:  J:142186 Lefebvre JL, et al., {gamma}-Protocadherins regulate neuronal survival but are dispensable for circuit formation in retina. Development. 2008 Dec;135(24):4141-51
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/30/2021
MGI 6.17
The Jackson Laboratory